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NIPT Test

NIPT Test

Non-Invasive Prenatal Test NIPT Test in Cyprus

What Is the NIPT Test?

The NIPT Test (Non-Invasive Prenatal Test) is an advanced prenatal screening method used during pregnancy to detect certain chromosomal abnormalities in the baby.

This test analyzes small fragments of fetal DNA, known as cell-free fetal DNA (cffDNA), that circulate in the mother’s bloodstream. By examining these DNA fragments, the NIPT Test can screen for several genetic conditions without the need for invasive procedures.

The test can be safely performed from the 10th week of pregnancy and requires only a simple blood sample from the mother.

At Dogus IVF Center in Cyprus, the NIPT Test is offered as part of comprehensive prenatal care to support the health of both mother and baby.

 

How Is the NIPT Test Performed?

The procedure is simple and completely safe for both mother and baby.

1. Blood Sample Collection

A small blood sample is taken from the expectant mother.

2. Laboratory Analysis

The sample is analyzed in specialized genetic laboratories using advanced sequencing technologies.

3. Fetal DNA Isolation

Cell-free fetal DNA is isolated from the maternal blood sample.

4. Chromosomal Screening

Genetic analysis is performed to screen for specific chromosomal abnormalities.

Because the NIPT Test only requires a blood sample, it carries no risk of miscarriage, unlike invasive procedures such as amniocentesis or chorionic villus sampling (CVS).

 

What Conditions Can the NIPT Test Detect?

The NIPT Test can screen for several common chromosomal abnormalities, including:

  • Trisomy 21 (Down Syndrome)
  • Trisomy 18 (Edwards Syndrome)
  • Trisomy 13 (Patau Syndrome)
  • Sex chromosome abnormalities

Depending on the testing panel selected, additional screening may include:

  • Microdeletion syndromes
  • Microduplication syndromes

Expanded testing panels allow broader genetic screening when medically appropriate.

 

Who Should Consider the NIPT Test?

Although the NIPT Test can be performed in most pregnancies, it is particularly recommended in certain situations:

  • Pregnancy at age 35 or older
  • Pregnancies achieved through IVF or ICSI treatment
  • Abnormal results in first-trimester screening tests
  • Previous pregnancy with a chromosomal abnormality
  • Suspicious findings during ultrasound examination
  • Twin pregnancies (in many cases)
  • Patients who prefer to avoid invasive diagnostic tests

A fertility specialist or obstetrician will evaluate the patient’s medical history before recommending prenatal screening options.

 

Advantages of the NIPT Test

High Accuracy

The NIPT Test is one of the most reliable prenatal screening methods available today, with accuracy rates approaching 99% for certain chromosomal conditions.

Safe for Mother and Baby

The test requires only a blood sample, meaning no risk of miscarriage.

Early Detection

Screening can be performed from the 10th week of pregnancy, allowing early evaluation of potential chromosomal abnormalities.

Early Gender Determination

Because fetal DNA is analyzed, the baby’s gender can often be determined early in pregnancy with high accuracy.

 

NIPT Testing Process

The testing process generally includes the following steps:

  1. Blood sample collection from the expectant mother
  2. Isolation of fetal DNA in a specialized laboratory
  3. Chromosomal screening analysis
  4. Test results usually available within 3–10 days
  5. Results reviewed and explained by fertility or genetic specialists

 

How Are NIPT Test Results Interpreted?

The NIPT Test is considered a screening test, not a definitive diagnostic test.

Results are typically reported in two categories:

Low Risk
The likelihood of the screened chromosomal conditions is very low, and routine pregnancy monitoring continues.

High Risk
If an increased risk is detected, confirmatory diagnostic tests such as amniocentesis or CVS may be recommended.

Genetic counseling may also be provided to help patients understand the results.

 

NIPT Test at Dogus IVF Center

At Dogus IVF Center Cyprus, the NIPT Test is offered as part of modern prenatal screening services.

Our specialists evaluate each patient individually and provide detailed guidance regarding genetic screening and follow-up care during pregnancy.

The goal is to combine advanced genetic technologies with personalized medical care to support healthy pregnancies.

Frequently Asked Questions About NIPT Test

Is the NIPT test reliable?
NIPT is an advanced genetic screening test based on the analysis of fetal DNA circulating in the mother’s blood. Using modern genetic technologies, it provides a high level of accuracy in detecting chromosomal abnormalities. However, NIPT is a screening test, and further diagnostic tests may be required for confirmation.
Does the NIPT test harm the baby?
No. NIPT is performed using a simple blood sample taken from the mother. Unlike invasive procedures such as amniocentesis, it carries no risk of miscarriage and is considered safe for both mother and baby.
When can the NIPT test be performed?
NIPT can be performed in early pregnancy, once sufficient fetal DNA is present in the mother’s bloodstream. This usually occurs from the early weeks of pregnancy onward.
Can NIPT be performed in twin pregnancies?
Yes. NIPT can be used in certain multiple pregnancies, including twins. However, the accuracy and scope of the test may vary depending on the specific characteristics of the pregnancy. Medical evaluation is essential.
Can the baby’s gender be determined with NIPT?
Yes. Since NIPT analyses fetal DNA, it can determine the baby’s sex with high accuracy. However, whether this information is included in the report depends on the selected test panel.
Can NIPT detect all genetic diseases?
No. NIPT screens for specific chromosomal abnormalities, but it cannot detect all genetic conditions. The scope of the test depends on the genetic panel used.
What happens if the NIPT result shows high risk?
If a high-risk result is detected, further diagnostic tests may be recommended to confirm the findings. These additional tests provide a definitive diagnosis.
How is pregnancy followed after NIPT?
If the result is low risk, pregnancy follow-up typically continues with routine check-ups. The doctor will determine the appropriate monitoring plan based on individual circumstances.
In which pregnancies is NIPT most recommended?
NIPT is particularly recommended in advanced maternal age, in patients with a history of genetic abnormalities, or when other screening tests indicate increased risk.
Can NIPT definitively diagnose Down syndrome?
NIPT can assess the risk of Down syndrome with high accuracy, but it is not a definitive diagnostic test. Confirmation may require further diagnostic procedures.
How long does it take to get NIPT results?
The turnaround time depends on the laboratory and testing method used. Results are typically available within a few days and are interpreted by a specialist.
Is NIPT mandatory?
No. NIPT is not mandatory. However, it is recommended for expectant mothers who wish to assess the risk of chromosomal abnormalities during pregnancy.

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