As IVF treatments continue to evolve to suit different family structures, the ROPA method—developed specifically for female couples—has become one of the most talked-about procedures in recent years.

ROPA treatment is regarded as a personalised version of traditional IVF procedures, and those wishing to learn more about the detailed process may also explore IVF treatment options in Cyprus.

What is the ROPA Method (Egg Retrieval from Partner)?

ROPA (Reception of Oocytes from Partner) is a specialised IVF method used for female couples.

In this technique:

• One partner acts as the egg donor (genetic mother).
• The other acts as the surrogate (the mother carrying the pregnancy).

In this way, both partners play a biological role at different stages of the process. ROPA is considered an advanced form of conventional IVF treatment.

How Does the ROPA Treatment Process Proceed?

The ROPA method requires a multidisciplinary approach and consists of the following stages:

1. Clinical Assessment and Planning

A detailed assessment of both partners’ hormonal profiles, ovarian reserve, and general health is carried out.

2. Ovarian Stimulation

The egg donor partner undergoes controlled ovarian stimulation

3. Oocyte Retrieval (OPU)

The mature eggs are retrieved under sedation.

4. Fertilisation

The retrieved oocytes are fertilised with sperm in a laboratory setting.

In female couples, donor sperm is typically used at this stage, and the procedure follows protocols similar to those used in sperm donation treatment.

 5. Embryo Transfer

The resulting embryos are transferred into the uterus of the partner who will carry the pregnancy.

6. Pregnancy Monitoring

The post-transfer process is closely monitored.

Who is the ROPA Method Suitable For?

ROPA treatment is particularly recommended in the following situations:

• Female couples
• When both partners wish to participate biologically in the process.
• When one partner has a better egg reserve.
• When the other partner is suitable for pregnancy.

Advantages of the ROPA Method

ROPA treatment offers significant advantages from both a medical and psychological perspective:

• Both partners’ involvement in the parenting process.
• Strengthening the bond between the couple.
• The creation of a personalised treatment plan.
• Separation of genetic and pregnancy roles.

Success Rates in the ROPA Method

Success rates depend on the following factors:

• The age of the egg donor partner
• Embryo quality
• The uterine environment
• Laboratory technology

Success rates in the younger age group are very close to those of conventional IVF treatments.

Costs of ROPA Treatment

The cost of ROPA treatment is generally higher than that of standard IVF due to its more complex structure and additional laboratory requirements.

Factors affecting the cost include:

• Medications used
•  Laboratory technology
• Sperm source
• Embryo freezing procedures

ROPA Treatment and Sperm Donation Explained

The ROPA method requires sperm for the fertilisation stage, which is provided through donor sperm.
As a result, the procedures involved and the criteria for donor selection are largely similar to those used in sperm donation treatment.

Careful selection of an appropriate donor can directly influence treatment success, particularly in terms of genetic compatibility and laboratory outcomes.

Is ROPA Treatment Safe?

The ROPA method is a safe and effective treatment when performed at experienced centres.

Key factors for success:

• A detailed assessment of both partners
• A personalised treatment plan
• An advanced embryology laboratory

The ROPA method is a robust treatment option for female couples, both biologically and emotionally.

To find out more about the process and learn about your personalised treatment plan, please contact us via our contact page.