Microsort Method

What Is the Microsort Method?

The Microsort Method is a sperm sorting technology used in fertility treatments to separate sperm cells according to the chromosome they carry.

Each sperm cell carries either an X chromosome or a Y chromosome.

• Sperm with an X chromosome may result in a female embryo
• Sperm with a Y chromosome may result in a male embryo

By separating these sperm populations before fertilization, doctors can increase the probability of conceiving a baby of the desired gender.

Clinical studies suggest that sperm sorting may achieve approximately:

• Up to 80% probability for male gender selection
• Up to 90% probability for female gender selection

This technology can be used together with fertility treatments such as IUI or Gender Selection IVF 

Microsort with IUI Treatment

One option involves using the sperm sorting technique together with IUI (Intrauterine Insemination).

During this treatment:

1. The female partner’s cycle is monitored to determine ovulation timing.
2. The sperm sample is processed in the laboratory and separated according to chromosome type.
3. The prepared sperm sample is placed directly into the uterus.

With this method:

• Couples wishing for a female baby may reach about 90% probability
• Couples wishing for a male baby may reach around 80% probability

However, overall pregnancy success also depends on factors such as female age, ovarian reserve, and reproductive health.

Microsort with IVF and ICSI

This sperm selection technology may also be combined with IVF treatment.

In this approach:

1. The ovaries are stimulated to produce multiple eggs.
2. Mature eggs are collected through egg retrieval (OPU).
3. The eggs are fertilized using sperm that has been separated in the laboratory.

Fertilization is usually performed using ICSI, where a single sperm cell is injected directly into the egg.

Because IVF allows closer laboratory control of fertilization, pregnancy rates are generally higher than with IUI-based treatments.

Combining Microsort with PGT

In some fertility treatments, sperm sorting may also be combined with PGT (Preimplantation Genetic Testing).

The process typically includes:

1. IVF egg retrieval
2. Fertilization with selected sperm
3. Genetic testing of embryos

PGT allows specialists to evaluate embryos for:

• Chromosomal abnormalities
• Embryo sex confirmation

When sperm sorting and genetic testing are used together, gender selection accuracy may reach up to 99%, while also helping identify genetically healthy embryos.

Advantages of Sperm Sorting Technology

This technique may provide several advantages during fertility treatment.

Possible benefits include:

• Increased probability of conceiving a baby of the desired gender
• More embryos of the preferred sex
• Greater flexibility when selecting embryos for transfer
• Opportunity to freeze additional embryos for future pregnancies

However, overall treatment success still depends on many factors such as maternal age, egg quality, embryo quality, and uterine health.

Microsort Method at Dogus IVF Center in Cyprus

At Dogus IVF Center, advanced reproductive technologies are used to support personalized fertility treatments.

Our medical and embryology teams evaluate each patient individually and determine whether sperm sorting techniques may be appropriate within the overall treatment plan.